H. Lee Moffitt Cancer Center and Research Institute, Inc.;University of South Florida
发明人:
Scott J. Antonia,James J. Mule
申请号:
US13892514
公开号:
US20130251752A1
申请日:
2013.05.13
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Described herein are methods of cancer immunotherapy, particularly compositions comprising genetically-modified cells that express macrophage colony stimulating factor (GM-CSF), CD40 ligand (CD40L), and chemokine C-C motif ligand 21 (CCL21), wherein the population of cells comprises bystander cells and target cancer cells, and methods of making these compositions and treating cancer using these compositions.