Alicia Regueiro-Ren,Zheng Liu,Jacob Swidorski,Ny Sin,Brian Lee Venables,Sing-Yuen Sit,Yan Chen,Jie Chen,Nicholas A. Meanwell
申请号:
US15015741
公开号:
US20160151387A1
申请日:
2016.02.04
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:These compounds are useful for the treatment of HIV and AIDS.