SWIDORSKI JACOB,VENABLES BRIAN LEE,LIU ZHENG,SIN NY,MEANWELL NICHOLAS A,REGUEIRO-REN ALICIA
申请号:
IN7859/DELNP/2015
公开号:
IN2015DN07859A
申请日:
2015.09.01
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Compounds having drug and bio affecting properties their pharmaceutical compositions and methods of use are set forth. In particular C 19 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors as represented by compounds of Formulas (I) and (II) wherein R1 is as defined herein and does not represent either an isopropyl or isopropenyl group: (Formula (I)) and (Formula (II)). These compounds are useful for the treatment of HIV and AIDS.