A method for producing magnetic resonance images of a subject in which artifacts resulting from a localized source, such as from pulsatile blood flow, are substantially mitigated is provided. The location of an artifact source, at which spins corresponding to flowing blood are located, is identified. Using this identified artifact source location, a region-of-saturation is calculated. A magnetic resonance imaging (MRI) system is then directed to perform a pulse sequence that results in the generation of a radio frequency (RF) saturation field being produced by an array of RF transmission coils. The RF saturation field is sized and shaped according to the calculated region-of-saturation. Images are reconstructed from image data acquired after application of the RF saturation field, and artifacts related to motion of the spins at the identified location of the artifact source are substantially mitigated in these images.