POLYMORPHES, FORMES SOLIDES DE (S)-2-((2-((S)-4-(DIFLUOROMETHYL)-2-OXOOXAZOLIDIN-3-YL)-5,6-DIHYDROBENZO[F]IMIDAZO[1,2-D][1,4]OXAZEPIN-9-YL)AMINO)PROPANAMIDE, ET PROCEDES DE PRODUCTION
CHAKRAVARTY, PAROMA,HAN, CHONG,KELLY, SEAN M.,NAGAPUDI, KARTHIK,SAVAGE, SCOTT
申请号：
CA3048591
公开号：
CA3048591A1
申请日:
2018.04.26
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to crystalline polymorph forms of (5)-2-((2-((5)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[]imidazo[ 1,2-J] [ 1,4]oxazepin-9-yl)amino)propanamide (GDC-0077), having the structure, Formula I or stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, and processes of preparing the polymorph forms.
