ERBB-2 TARGETING AGENT AND A BISPECIFIC ANTIBODY WITH ANTIGEN-BINDING SITES THAT BIND AN EPITOPE ON AN EXTRACELLULAR PART OF ERB-2 AND ERBB-3, FOR TREATMENT OF AN INDIVIDUAL WITH AN ERBB-2, ERBB-2/ERBB-3 POSITIVE TUMOUR
THROSBY, Mark,GEUIJEN, Cecilia Anna Wilhelmina,MAUSSANG-DETAILLE, David Andre Baptiste,LOGTENBERG, Ton
申请号：
SG11201908833T
公开号：
SG11201908833TA
申请日:
2018.04.03
申请国别(地区):
SG
年份:
2019
代理人:
摘要：
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 October 2018 (04.10.2018) WIPO I PCT o mons °nolo ono! mu HE Imo oimIE (10) International Publication Number WO 2018/182421 Al (51) International Patent Classification: A61K 39/395 (2006.01) C07K 16/46 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) CO7K 16/32 (2006.01) (21) International Application Number: PCT/NL2018/050205 (22) International Filing Date: Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) 03 April 2018 (03.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 17164396.8 31 March 2017 (31.03.2017) EP 15/476,260 31 March 2017 (31.03.2017) US (71) Applicant: MERUS N.V. [NL/NL]； Yalelaan 62, 3584 CM Utrecht (NL). (72) Inventors: THROSBY, Mark； c/o Yalelaan 62, 3584 CM Utrecht (NL). GEUIJEN, Cecilia Anna Wilhelmina； c/o Yalelaan 62, 3584 CM Utrecht (NL). MAUSSANG-DE- TAILLE, David Andre Baptiste； c/o Yalelaan 62, 3584 CM Utrecht (NL). LOGTENBERG, Ton； c/o Yalelaan 62, 3584 CM Utrecht (NL). (74) Agent: JANSEN, CM.； V.O., Carnegieplein 5, 2517 KJ Den Haag (NL). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicate
