APPLICATION DE DERIVES SUBSTITUES DU CINNAMAMIDE DANS LA PREPARATION DE MEDICAMENTS CONTRE L'ANXIETE

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专利权人:

TASLY PHARMACEUTICAL GROUP CO.; LTD.

发明人:

HAN, MIN,MA, XIAOHUI,ZHOU, WANGYI,LIU, YANYONG,LI, YANCHUAN,WANG, JING,ZHOU, SHUIPING,SUN, HE,ZHU, YONGHONG

申请号：

CA3007870

公开号：

CA3007870A1

申请日:

2017.01.20

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Disclosed is an application of substituted cinnamamide derivatives in the preparation of Anti-anxiety medications, the substituted cinnammide derivatives are compounds having the structure of formula (I) or pharmaceutically acceptable salts thereof, wherein, R1 is H, -OH, -F, -Cl, -Br, -I, -OCH 3, -OCF 3, -OCHF 2, -OCH 2F, -CF 3, -CHF 2, -CH 2F, -CH 3, -CH 3CH 2, -CF 3CH 2, -CN, -NO 2, -NH 2 or -COOR 5； R 2 is H, C 1-C 10 linear alkyl, C 3-C 10 branched alkyl, C 3-C 10 cyclic alkyl, C 1-C 10 hydroxyalkyl or a N-substituted piperazine-derived group； or R 2 is a group forming with adjacent Y a tetrahydropyrrolyl group, a piperidyl group or a cyclohexanimido group.

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