APPLICATION DE DÉRIVÉS SUBSTITUÉS DU CINNAMAMIDE DANS LA PRÉPARATION DE MÉDICAMENTS CONTRE L'ANXIÉTÉ

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专利权人:

Tasly Pharmaceutical Group Co.; Ltd.

发明人:

HAN, Min,MA, Xiaohui,ZHOU, Wangyi,LIU, Yanyong,LI, Yanchuan,WANG, Jing,ZHOU, Shuiping,SUN, He,ZHU, Yonghong

申请号：

EP17743676

公开号：

EP3409664A4

申请日:

2017.01.20

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed is an application of substituted cinnamamide derivatives in the preparation of anti-anxiety medications, the substituted cinnammide derivatives are compounds having the structure of formula (I) or pharmaceutically acceptable salts thereof, wherein, R 1 is -H, -OH, -F, -Cl, -Br, -I, -OCH 3 , -OCF 3 , -OCHF 2 , -OCH 2 F, -CF 3 , -CHF 2 , -CH 2 F, -CH 3 , -CH 3 CH 2 , -CF 3 CH 2 , -CN, -NO 2 , -NH 2 or -COOR 5 ； R 2 is H, C 1 -C 10 linear alkyl, C 3 -C 10 branched alkyl, C 3 -C 10 cyclic alkyl, C 1 -C 10 hydroxyalkyl or a N-substituted piperazine-derived group； or R 2 is a group forming with adjacent Y a tetrahydropyrrolyl group, a piperidyl group or a cyclohexanimido group.

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中国工程科技知识中心

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