Compositions and methods for treatment of the back of the eye

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专利权人:

アラーガン、インコーポレイテッド

发明人:

ロバート・ティ・ライオンズ,ジェイムズ・エヌ・チャン,ジョン・ティ・トログデン,スコット・エム・ホイットカップ

申请号：

JP2011183912

公开号：

JP5592321B2

申请日:

2011.08.25

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

A composition formulated for injection into a posterior segment of an eye of a human or animal comprising a corticosteroid component present in a therapeutically effective amount, wherein said corticosteroid component has a solubility in water at 25°C of less than 10 mg/ml, and wherein said corticosteroid component is present in a plurality of particles； a viscosity inducing component in an amount effective to increase the viscosity of the composition； and an aqueous carrier component, wherein the viscosity inducing component is selected from the group consisting of hyaluronic acid, metal hyaluronates, carbomers, polyacrylic acid, cellulosic derivatives, polycarbophil, gelatin, dextrin, polysaccharides, polyacrylamide, polyvinyl alcohol, polyvinyl acetate and mixtures thereof； and wherein the composition includes no added preservative component.

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