SUSAN GREGORY;DAVID TUNG;JEFFREY R. CROSBY;MAUSUMEE GUHA;JAMES G. KARRAS;SUSAN M. FREIER;KENNETH W. DOBIE
发明人:
JAMES G. KARRAS,SUSAN GREGORY,JEFFREY R. CROSBY,MAUSUMEE GUHA,DAVID TUNG,SUSAN M. FREIER,KENNETH W. DOBIE
申请号：
US13408646
公开号：
US20120316221A1
申请日:
2012.02.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation.
