Susan Gregory;Mausumee Guha;James G. Karras;David Tung;Jeffrey R. Crosby;Susan M. Freier
发明人:
James G. Karras,Susan Gregory,Jeffrey R. Crosby,Mausumee Guha,David Tung,Susan M. Freier
申请号：
US11816705
公开号：
US08153603B2
申请日:
2006.02.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation.
