A strain of a probiotics lactic acid bacterium selected from the strains having the following properties (1) to (7) among the lactic acid bacteria originally isolated from adult human feces: (1) they have high resistance against gastric acids/bile acids； (2) they can highly promote the IL-12 production from murine spleen cells and can highly improve the Th1/Th2 balance in the murine spleen cells； (3) they can highly inhibit the antigen-specific IgE production induced by intraperitoneal administration of ovalbumin to a BALB/c mouse； (4) they can highly inhibit the antigen-specific IgE production induced by the oral administration of a food antigen to a C57BL/6N mouse； (5) they can highly activate natural killer cells； (6) they can highly promote the IL-12 production and can highly improve the Th1/Th2 balance in spleen cells and mesenteric lymph node cells from a mouse immunized with ovalbumin； and (7) they can highly inhibit the eosionophilla induced by an antigen extracted from cedar pollen.
