Andrew Chwee Aun WAN,Jia Kai LIM,Vivian Yujing LIM,Nina MA,Siti Thaharah MOHAMED
申请号:
US15306045
公开号:
US20170121687A1
申请日:
2015.04.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a method for reprogramming a first cell type to an intermediate cell of a second cell type comprising the step of contacting the first cell with a first agent to modulate an integrin profile in the first cell type to provide an intermediate cell of the second cell type. The present invention also relates to a reprogrammed cell obtained by the method of the invention, a kit for reprogramming a first cell type to a second cell type as well as methods for treating a patient in need of cell based therapy, tissue replacement and cancer therapy.