Calitor Sciences, LLC;Sunshine Lake Pharma Co., Ltd.
发明人:
XI, Ning
申请号：
ES12752321
公开号：
ES2590778T3
申请日:
2012.02.21
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
A compound of formula (I): ** Formula ** or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate or a pharmaceutically acceptable salt thereof, in which: R1 is C2 hydroxyalkoxy -6, R2 is H or methoxy, R3 is H or F, R4 is H, F, Cl, Br, I, CN, C1-3 haloalkyl, C2-5 heterocyclyl, C2-5 heterocyclyl-C1-3 alkyl, cycloalkyl C3-6 or C3-6 cycloalkyl-C1-3 alkyl and X is CH or N, wherein the hydroxyalkoxy is a linear or branched alkoxy radical substituted with one or more hydroxyl radicals.Un compuesto de formula (I):**Fórmula** o un estereoisomero, un isomero geometrico, un tautomero, un N-oxido, un hidrato, un solvato o una sal farmaceuticamente aceptable del mismo, en la que: R1 es hidroxialcoxi C2-6, R2 es H o metoxi, R3 es H o F, R4 es H, F, Cl, Br, I, CN, haloalquilo C1-3, heterociclilo C2-5, heterociclil C2-5-alquilo C1-3, cicloalquilo C3-6 o cicloalquil C3-6-alquilo C1-3 y X es CH o N, en donde el hidroxialcoxi es un radical alcoxil lineal o ramificado sustituido con uno o mas radicales hidroxilo.
