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COMPOSE PHARMACEUTIQUE
专利权人:
MERCK SHARP & DOHME CORP.;IOMET PHARMA LTD.
发明人:
COWLEY, PHILLIP M.,HAN, YONGXIN
申请号:
CA2998186
公开号:
CA2998186A1
申请日:
2016.09.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided is a compound having formula (I): wherein R2 is selected from -C1, -Br and -CN; R1 and R4 are independently selected from H and -F; R631, R632, R641 and R642 are independently selected from -H, -F and substituted or unsubstituted C1-C3 alkyl groups; and R651 and R652 are independently selected from H and substituted or unsubstituted C1-C3 alkyl groups and substituted or unsubstituted phenyl groups; and wherein at least one of R631, R632, R641, R642 and R652 is not -H, or wherein when all of R631, R632, R641, R642 and R652 are -H, R651 is not Me or Et.
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