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Modified live flavobacterium strains, stabilized vaccines comprising same, and methods of making and use thereof
专利权人:
Auburn University
发明人:
Oscar Olivares-Fuster,Covadonga R. Arias
申请号:
US14169976
公开号:
US09161972B2
申请日:
2014.01.31
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides attenuated F. columnare strains that elicit an immune response in an animal, particularly a fish, against virulent F. columnare compositions comprising said strains, methods of vaccination against F. columnare, and kits for use with such methods and compositions. The invention further relates to a stabilization buffer, which allows the attenuated compositions to remain storage stable at ambient temperatures for extended periods of time.
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