Concomitant drugs containing probucol and tetrazolylalkoxy-dihydrocarbostyril derivatives having superoxide inhibitory effect

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专利权人:

大塚製薬株式会社

发明人:

ホン・キワン,吉川 智博

申请号：

JP2012199804

公开号：

JP5603393B2

申请日:

2012.09.11

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

This invention relates to a combination drug comprising a combination of a tetrazolylalkoxy-dihydrocarbostyril derivative of the formula: wherein R is cycloalkyl, A is lower alkylene, and the bond between 3-and 4-positions of carbostyril nucleus is single bond or double bond, or a salt thereof and Probucol, which is useful for preventing and treating cerebral infarction including acute cerebral infarction and chronic cerebral infarction, arteriosclerosis, renal diseases (e.g. diabetic nephropathy, renal failure, nephritis), and diabetes owing to synergistic superoxide suppressant effects of the combination.

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