Novel uses of Pipoxolan HCl and its pharmaceutical preparations are disclosed. Pipoxolan is useful therapeutic drugs for pathological conditions caused by coronary artery spasm which reduce myocardial blood flow, and lead to myocardial ischemia, the syntoms including: chest pain, chest tightness, arrhythmia, stenocardia, angina pectoris, myocardial infarction, and sudden death…clinical syndromes. The pharmaceutical preparations which contain Pipoxolan HCl can cure and prevent those symptoms.本發明關於一種Pipoxolan(匹普蘇蘭)之新穎用途及基於此新穎用途的藥品製劑。Pipoxolan(匹普蘇蘭)能用於製備由冠狀動脈痙攣引起的病理症狀況之治療與預防性藥物,以治療與預防冠狀動脈痙攣導致心肌血流量降低,造成心肌缺血,所引起包括胸痛、胸悶、心律失常、心絞痛、心肌梗塞及猝死等臨床綜合症。含Pipoxola(匹普蘇蘭)成分的藥品製劑可以治療及預防冠狀動脈痙攣導致之上述症狀。