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Biphasic lipid-vesicle composition and method for treating cervical dysplasia by intravaginal delivery
专利权人:
Helix BioPharma Corp.
发明人:
Docherty, John M.,Foldvari, Marianna,Kumar, Praveen
申请号:
AU2008234364
公开号:
AU2008234364B2
申请日:
2008.03.27
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
A biphasic lipid vesicle composition for treating cervical displasia by intravaginaldelivery. The composition includes a suspension of lipid-bilayer vesicleshaving entrapped therein, an oil-in-water emulsion, human interferon alpha-2band L-methionine, the composition having an interferon alpha-2b specific activityof between about 1-10 MIU (million international units) per gram composition,and between 0.01 to 0.5 weight percent L-methionine. In the treatment method,the composition is administered at a dose of between about 1- 20 MIU interferonalpha-2b, and this dose is administered at least 3 days/week, for a period of atleast 4 weeks.
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