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BIPHASIC LIPID-VESICLE COMPOSITION AND METHOD FOR TREATING CERVICAL DYSPLASIA BY INTRAVAGINAL DELIVERY
专利权人:
Praveen KUMAR;Marianna FOLDVARI;John M. DOCHERTY
发明人:
Marianna FOLDVARI,Praveen KUMAR,John M. DOCHERTY
申请号:
US13849451
公开号:
US20130216610A1
申请日:
2013.03.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A biphasic lipid vesicle composition for treating cervical displasia by intravaginal delivery. The composition includes a suspension of lipid-bilayer vesicles having entrapped therein, an oil-in-water emulsion, human interferon alpha-2b and L-methionine, the composition having an interferon alpha-2b specific activity of between about 1-10 MIU (million international units) per gram composition, and between 0.01 to 0.5 weight percent L-methionine. In the treatment method, the composition is administered at a dose of between about 1-20 MIU interferon alpha-2b, and this dose is administered at least 3 days/week, for a period of at least 4 weeks.
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