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METHOD FOR PRODUCING PHARMACEUTICAL TABLET
专利权人:
TORAY INDUSTRIES; INC.
发明人:
SUZUKI, HIROSHI,YOSHINARI, TOMOHIRO
申请号:
EP08752993
公开号:
EP2156838A4
申请日:
2008.05.20
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A process for advantageously producing tablets having an improved release property and an excellent stability to change with time is provided. The process is for producing tablets containing a morphinan compound represented by the Formula (I) below or pharmaceutically acceptable acid addition salt thereof and an acidic substance such as fumaric acid, maleic acid or adipic acid, and characterized in that the morphinan compound or a pharmaceutically acceptable acid addition salt thereof is granulated by wet granulation together with (an) excipient(s) prior to adding the acidic substance thereto.
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