Salts of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same

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专利权人:

INCYTE CORPORATION

发明人:

WENG LINGKAI,QIAO LEI,ZHOU JIACHENG,LIU PINGLI,PAN YONGCHUN

申请号：

NZ60279109

公开号：

NZ602791A

申请日:

2009.05.20

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

ABSTRACT - 602791 The disclosure relates to a process of preparing a compound of Formula (I) or salt thereof: comprising reacting a compound of Formula (II) with a compound of Formula (III) to form a compound of Formula (I), or salt thereof wherein the process further comprises preparing the compound of Formula (II) by a process comprising reacting a compound of Formula (IIa) with a compound of Formula (IIb) for a length of time sufficient to generate a compound of Formula (II), wherein X1 is chloro, bromo, or iodo and wherein the reacting of the compound of Formula (IIa) with the compound of Formula (IIb) is carried out in the presence of proline.

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