The present invention relates a pharmaceutical composition comprising pyridino pyrimidine derivatives or medical salt thereof. Specifically, the present invention relates a pharmaceutical composition comprising 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperidin -4-yl) pyridin-2-yl) amino) pyridino [2,3-d] pyrimidin-7(8H)-one or its pharmacologically acceptable salts and disintegrant, the disintegrant is without metallic element, the composition The composition dissolves rapidly. The preparation process of the pharmaceutical composition is simple, and is more suitable for large-scale production.本發明公開了一種含有吡啶并嘧啶類衍生物或其可藥用鹽的醫藥組成物。具體而言，該組成物包含6-乙醯基-8-環戊基-5-甲基-2-((5-(哌啶-4-基)吡啶-2-基)胺基)吡啶并[2,3-d]嘧啶-7(8H)-酮或其藥理學上可接受的鹽，以及崩解劑，該崩解劑為不含金屬元素的崩解劑，該組成物溶出迅速。本發明的醫藥組成物製備工藝簡單，更適合工藝化大生產。
