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СТАБИЛЬНАЯ ИНЪЕКЦИОННАЯ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ЭПИНЕФРИНА ИЛИ ЕГО СОЛЕЙ
专利权人:
ВОКХАРДТ ЛИМИТЕД (IN)
发明人:
ГУПТА Амит (IN),НАГОРИ Раджендра Нандлал (IN),МЕРВАДЕ Арвинд Йеканатхса (IN),ДЭО Кешав (IN),ДЖАИН Гириш Кумар (IN)
申请号:
RU2015117254
公开号:
RU2015117254A
申请日:
2013.05.03
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. Stabilized pharmaceutical composition injectable epinephrine or a salt thereof containing sodium metabisulfite, wherein the ratio of the amount of epinephrine or its salt to sodium metabisulphite in the composition is from about 1: 0,005 to about 1: 1.5 by weight, characterized in that said composition It contains epinephrine having a purity equal to or greater than 98% by masse.2. Stabilized pharmaceutical composition epinephrine injection, containing sodium metabisulfite, wherein the ratio of the amount of epinephrine or its salt to sodium metabisulphite in the composition is from about 1: 0,005 to about 1: 1.5 by weight, wherein the total amount of impurities in said composition is less than 4% .3. Stabilized pharmaceutical composition epinephrine injection, containing sodium metabisulfite, wherein the ratio of the amount of epinephrine or its salt to sodium metabisulphite in the composition is from about 1: 0,005 to about 1: 1.5 by weight, characterized in that said composition contains no one impurity in an amount exceeding 3% .4. The stabilized injectable pharmaceutical composition epinephrine or a salt thereof containing sodium metabisulfite, wherein the ratio of the amount of epinephrine or its salt to sodium metabisulphite in the composition is from about 1: 0,005 to about 1: 1.5 by weight, characterized in that said composition is substantially It contains excess epinefrina.5. The stabilized injectable pharmaceutical composition according to Claim. 1, wherein the composition comprises a sulphonate epinephrine in an amount of about 3.0% or less at SVA 0,15.6. The stabilized injectable pharmaceutical composition according to Claim. 1,1. Стабилизированная инъекционная фармацевтическая композиция эпинефрина или его соли, содержащая метабисульфит натрия, в которой отношение количества эпинефрина или его соли к метабисульфиту натрия в композиции составляет от примерно 1:0,005 до примерно 1:1,5 по массе, отличающаяся тем, что указанная композиция содержит эпин
来源网站:
中国工程科技知识中心
来源网址:
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