A Foley catheter drainage collection system which is capable of permitting the removal and reconnection of drainage bags without compromising the sterility of the drainage system lumen. The collection system has a tubing element which includes a drainage valve associated with an end thereof remote from the insertion end of a Foley catheter. The drainage valve associated with the tubing element is movable from an open catheter drainage position to a closed position. The collection system also includes a drainage bag having a first connector element associated therewith and a second connector element is associated with the drainage valve. The second connector element is adapted for mating engagement with the first connector element. The collection system further includes a retaining element for maintaining the connector elements in mating engagement when the drainage valve is disposed in the open catheter drainage position.