ONCOLYTIC VIRAL VECTORS AND USES THEREOF

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专利权人:

Inc.;Oncorus

发明人:

Kenneth P. GREENBERG,Mitchell H. FINER

申请号：

US16047499

公开号：

US20180339004A1

申请日:

2018.07.27

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present disclosure relates to recombinant viral vectors for the treatment and prevention of cancer. Oncolytic viral vectors incorporate one or more of the following features: viral replication restriction by insertion of tumor-suppressive microRNA (miRNA) target sequences into the viral genome； disruption of oncogenic miRNA function； cancer microenvironment remodeling； and cancer cell targeting by incorporation of protease-activated antibodies into the viral particle.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/