NOUVEL INHIBITEUR DE LA KINASE FLT3 ET UTILISATION DE CE DERNIER

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专利权人:

Hefei Cosource Pharmaceutical Co., Ltd.;Hefei Institutes of Physical Sicence, Chinese Academy of Sciences;Hefei Institutes of Physical Sicence; Chinese Academy of Sciences

发明人:

LIU, Jing,LIU, Qingsong,LI, Xixiang,WANG, Aoli,WU, Hong,CHEN, Cheng,WANG, Wenchao,HU, Chen,ZHAO, Zheng,WU, Jiaxin,LIU, Juan,YU, Kailin,WANG, Wei,WANG, Li,WANG, Beilei

申请号：

EP15878539

公开号：

EP3248979A4

申请日:

2015.08.07

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/