CHIU, PETER JS,邱 俊雄,HSU, MEI CHI,许美智,許美智,SHIH, YING CHU,石英珠,WU, EDWIN SC,吴 森洲,吳 森洲,邱 俊雄,吴 森洲,吳 森洲
申请号：
TW105109186
公开号：
TW201639572A
申请日:
2016.03.24
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
The present invention relates to new medical uses of morphinans such as naltrexone, nalmefene and their related derivatives. The present invention relates to Toll-like receptor 4 (TLR4) antagonist compounds, and pharmaceutical formulations thereof, and use thereof for prevention and treatment of autoimmune liver diseases including but not limited to autoimmune hepatitis.本發明有關於嗎啡喃(諸如納曲酮、納美芬和它們的相關衍生物)的新醫學用途。本發明有關於類鐸受體4(TLR4)拮抗劑化合物和它們的藥學配方，以及它們用於預防和治療自體免疫肝臟疾病(包括但不限於自體免疫肝炎)的用途。
