The Board of Regents of the University of Texas System
发明人:
Renata PASQUALINI,Wadih ARAP,Juri GELOVANI,Frank C. MARINI, III,Amin HAJITOU,Mian ALAUDDIN,Martin TREPEL
申请号:
US15790866
公开号:
US20180256740A1
申请日:
2017.10.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Embodiments of the invention are generally directed to compositions and methods of delivering one or more transgene to a target cell, such as a tumor cell, in a site-specific manner to achieve enhanced expression and to constructs and compositions useful in such applications. In certain aspects, expression from a therapeutic nucleic acid may be assessed prior to administration of a treatment or diagnostic procedure to or on a subject.