Frank C. Marini, III;Mian Alauddin;Renata Pasqualini;Amin Hajitou;Martin Trepel;Juri Gelovani;Wadih Arap
发明人:
Renata Pasqualini,Wadih Arap,Juri Gelovani,Frank C. Marini, III,Amin Hajitou,Mian Alauddin,Martin Trepel
申请号：
US13403765
公开号：
US09827327B2
申请日:
2012.02.23
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Embodiments of the invention are generally directed to compositions and methods of delivering one or more transgene to a target cell, such as a tumor cell, in a site-specific manner to achieve enhanced expression and to constructs and compositions useful in such applications. In certain aspects, expression from a therapeutic nucleic acid may be assessed prior to administration of a treatment or diagnostic procedure to or on a subject.
