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ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ НА ОСНОВЕ N-КАРБАМОИЛА-МЕТИЛ-4-ФЕНИЛ-2-ПИРРОЛИДОНА
专利权人:
Общество с ограниченной ответственностью "ВАЛЕНТА-ИНТЕЛЛЕКТ" (RU)
发明人:
Фазылов Марат Феликсович (RU)
申请号:
RU2012136578/15
公开号:
RU2012136578A
申请日:
2012.08.28
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical composition based on N-carbamoyl-methyl-4-phenyl-2-pyrrolidone (Phenotropil ™), wherein the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is about 90% by weight of the composition lactose monohydrate in an amount of 3-10% by weight of the composition carboxymethylcellulose in an amount of 2-5% by weight of the composition polyvinylpyrrolidone in an amount of 2-5% by weight of the composition and stearic acid salt in an amount of 0.2-2.0% by weight kompozitsii.2. A composition according to claim 1, wherein the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the levorotatory isomer of N-carbamoyl-methyl-4-phenyl-2-pirrolidona.3. A composition according to claim 1, wherein the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the dextrorotatory isomer of N-carbamoyl-methyl-4-phenyl-2-pirrolidona.4. A composition according to claim 1, wherein the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is a mixture of racemic N-carbamoyl-methyl-4-phenyl-2-pirrolidona.5. A composition according to claim 1, characterized in that it can further comprise krahmal.6. A composition according to claim 1, characterized in that is in the form tabletki.7. Pharmaceutical composition based on N-carbamoyl-methyl-4-phenyl-2-pyrrolidone, comprising a N-carbamoyl-methyl-4-phenyl-2-pyrrolidone, lactose monohydrate, carboxymethylcellulose, polyvinylpyrrolidone and stearic acid salt in which N- carbamoyl-methyl-4-phenyl-2-pyrrolidone in an amount of 70-80% by weight kompozitsii.8. A composition according to claim 7, wherein the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the levorotatory isomer of N-carbamoyl-methyl-4-phenyl-2-pirrolidona.9. A composition according to claim 7, wherein the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the dextrorotatory isomer of N-carbamoyl1. Фармацевтическая композиция на основе N-карбамоил-метил-4-фенил-2-пирролидона (Фенотропил™), в которой N-карбамоил-метил-4-фенил-2-пирролидон составляет около 90% от массы композиции моногидрат лактозы, в количестве 3-10% от
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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