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BACTERIUM PRODUCING DHA AND EPA, 6 GENE FRAGMENTS OF GENOME OF BACTERIUM AND USE THEREOF
专利权人:
XIAMEN HUISON BIOTECH CO., LTD.
发明人:
CHEN, Liyi,ZHONG, Huichang,CHEN, Shuirong
申请号:
WO2018CN87613
公开号:
WO2018219171(A1)
申请日:
2018.05.21
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
Disclosed are a bacterium producing DHA and/or EPA, 6 gene fragments of the genome of the bacterium and the use thereof. The bacterium is Schizochytrium limacinum HS01 with the deposit number in China General Microbiological Culture Collection Center being CGMCC No.13746. The 6 gene fragments consist of gene fragment 1 to gene fragment 6, and the nucleotide sequences are sequentially as shown in sequence 3 to sequence 8 of the sequencing listing. Experiments prove that, a fermentation broth containing DHA and EPA is obtained through fermentation cultivation of Schizochytrium limacinum HS01; the gene fragments 1-6 are introduced into the Schizochytrium limacinum MYA-1381 to obtain a recombinant bacterium; and the capability of the recombinant bacterium to produce DHA and EPA is greatly improved. The bacterium, 6 gene fragments, proteins encoded by the 6 gene fragments, and a vector, cell or organism containing the 6 gene fragments provided by the present invention all have an important application value.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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