Binder, Joseph John,Cho, Helen Kim,Dermyer, Michael Robert,Jooss, Karin Ute,Pierce, Brian Gregory,Tan, Joyce Tsi,Tsai, Van To
申请号:
NZ74174213
公开号:
NZ741742A
申请日:
2013.04.29
申请国别(地区):
NZ
年份:
2019
代理人:
摘要:
The present disclosure provides a pharmaceutical product comprising (1) a vaccine comprising an antigen construct, and (2) a CTLA-4 inhibitor, wherein the antigen construct comprises a nucleotide sequence encoding an immunogenic PSMA polypeptide selected from the group consisting of: (i) a polypeptide consisting of amino acids 15-750 of the amino acid sequence of SEQ ID NO: 1; and (ii) a polypeptide comprising the amino acid sequence of SEQ ID NO: 9.