GREEN BIOMED, INC.;KIRIN HOLDINGS KABUSHIKI KAISHA
发明人:
SEKIKAWA, KENJI
申请号：
CA3086456
公开号：
CA3086456A1
申请日:
2018.12.21
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention provides a fusion polypeptide that induces a humoral immune response and a cellular immune response to a virus. The fusion polypeptide has an oligomerization activity and contains an antigen or fragment thereof according to (a) and an antigen or fragment thereof according to (b) as follows: (a) a viral antigen or fragment thereof, that contains a B-cell epitope that is conserved between subtypes of the virus, and (b) a viral antigen or fragment thereof, that contains a T-cell epitope that is conserved between subtypes of the virus (here, the antigen or fragment thereof according to (a) and/or (b) has an oligomerization activity, or the fusion polypeptide further contains, in addition to the antigens or fragments thereof according to (a) and (b), (c) a polypeptide having an oligomerization activity).
