A process for producing purified theaflavin extract is provided which comprises combining an organic solvent with tea leaves, extracting polyphenols from the tea leaves to produce an organic stock substrate solution； producing a second batch of tea leaves； grinding the second batch of tea leaves to produce stock fermentation enzyme； combining the stock substrate solution with the stock fermentation enzyme to produce a fermentation mixture； fermentation of the mixture to produce theaflavins； and, separating the theaflavins from the fermentation mixture to produce purified theaflavin extract. Oral dosage forms are provided which comprise an effective amount of the purified theaflavin extract. Methods of treatment of human physiological disorders are provided which comprise administering an oral dosage form.
