THE UNIVERSITY OF BRITISH COLUMBIA UNIVERSITY-INDUSTRY LIAISON OFFICE;BRITISH COLUMBIA CANCER AGENCY BRANCH
发明人:
ANDERSEN, RAYMOND JOHN,BANUELOS, CARMEN ADRIANA,FERNANDEZ, JAVIER GARCIA,MAWJI, NASRIN R.,SADAR, MARIANNE DOROTHY,WANG, JUN
申请号:
CA2911352
公开号:
CA2911352A1
申请日:
2014.05.09
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Compounds having a structure of Structure I or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein R1, R2, R3, R4, R5, J1, J2, X, Z, n1and n2 are as defined herein, and wherein at least one of R1, R2 or R3 is an alkyl, alkenyl, aryl or aralkyl ester, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.