THOMAS LANGGUTH,DR. STEFAN BRACHT,PROF. DR. MICHAEL DITTGEN,PETRA HUBER,DIRK SCHENK
申请号：
MYPI 2010001448
公开号：
MY152750A
申请日:
2010.03.31
申请国别(地区):
MY
年份:
2014
代理人:
摘要：
THE PRESENT INVENTION RELATES TO A PATCH COMPRISING A DRUG-CONTAINING LAYER WITH LOW CONTENT OF HORMONES, SUCH AS GESTODENE, AND OPTIONALLY AN ESTROGEN (E.G. ETHINYL ESTRADIOL). UPON ADMINISTERING THE PATCH TO A WOMAN, PLASMA LEVELS OF AT LEAST 1.0 NG/ML OF GESTODENE IS ACHIEVED AT STEADY STATE CONDITIONS WITHOUT THE NEED OF INCORPORATING PENETRATION ENHANCERS OR PERMEATION ENHANCERS IN THE DRUG-CONTAINING LAYER. SATISFACTORITY PLASMA LEVELS OF THE HORMONES IS ALSO ACHIEVED THROUGHOUT A PERIOD OF AT LEAST 1 WEEK, MAKING THE PATCH APPLICABLE FOR BEING USED IN FEMALE CONTRACEPTION WITH THE CONCEPT OF ADMINISTERING THE PATCH ONES WEEKLY.
