CHUGAI SEIYAKU KABUSHIKI KAISHA;SEIKO YAMAMOTO;ISAMU TERASHIMA;HIROYUKI DOI
发明人:
SEIKO YAMAMOTO,HIROYUKI DOI,ISAMU TERASHIMA
申请号：
IL25466817
公开号：
IL254668D0
申请日:
2017.09.25
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
The present invention provides a method of cell culture comprising adding a cell-containing seed medium to an initial medium and starting to culture the cell in the initial medium, wherein the initial medium has an organism-derived culture medium additive added thereto and the amount of the C-terminal amidated species in the produced protein is controlled by the copper content of the initial medium at the start of cell culture.
