Provided are an LED-based skin treatment system capable of performing a skin treatment in consideration of individuals' respective skin properties and a reaction of skin to a change in a patient's emotional state by using an LED light source, and a method thereof. The LED-based skin treatment system includes a skin diagnosis unit ascertaining a patient's skin properties and an extent of a skin reaction to a change in a patient's emotional state by using multiple sensors, and diagnosing a skin lesion and an extent thereof and a skin lesion occurrence location; a skin treatment unit controlling an output state of an LED light source according to the skin lesion and the extent thereof and the skin lesion occurrence location; and a hardware control unit driving the multiple sensors and the LED light source.