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DÉRIVÉ D'INDOLE, ET SEL DE QUALITÉ PHARMACOLOGIQUE DE CELUI-CI
专利权人:
Kissei Pharmaceutical Co., Ltd.;Kyorin Pharmaceutical Co., Ltd.
发明人:
申请号:
EP12739875.8
公开号:
EP2669272A1
申请日:
2012.01.24
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention provides a compound represented by the general formula (I) of the present invention, which has EP1 receptor antagonism:[wherein A represents a benzene ring, a pyridine ring, or the like; Y1 represents a C1-6 alkylene group or the like; Y2 represents a single bond or the like; Z represents -C(=O)-NHSO2R6, an acidic 5-membered hetero ring group, or the like; R1 represents a hydrogen atom or the like; R2 represents a phenyl group, a 5-membered aromatic heterocyclic group, or the like; R3 represents a halogen atom, a C1-6 alkoxy group, or the like; R4 represents a hydrogen atom, a halogen atom, or the like; R5 represents a hydrogen atom or the like; and R6 represents a C1-6 alkyl group or the like], or a pharmaceutically acceptable salt thereof. Furthermore, the compound (I) of the present invention can be used as an agent for treating or preventing LUTS, in particular, various symptoms of OABs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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