SOURENA, NADJI,SMOOT, JAMES T.,VANARTSDALEN, JOSEPH A.
申请号：
CA2777099
公开号：
CA2777099C
申请日:
2010.07.30
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions.
