Compound of formula I ** Formula ** or pharmaceutically acceptable salts and esters thereof, wherein: Q is carbon or nitrogen； R1 is hydrogen or C1-7 alkyl optionally substituted by halogen； R2 and R3 are attached to the ring containing Q by substitution of a hydrogen atom of a ring carbon atom； and R2 and R3 are independently selected from the group consisting of: (1) hydrogen； (2) halogen； (3) -NH2； (4) -NO2； (5) C1-7 alkyl optionally substituted by halogen, (6) C3-7 cycloalkyl optionally substituted by lower alkyl； (7) C2-7 alkenyl； (8) C2-7 alkynyl； 20 (9) C1-7 alkanoyl； (10) C1-7 alkoxy； (11) C3-7 cycloalkoxy； (12) lower heterocycloalkyl； (13) lower heterocycloalkyloxy； (14) C1-7 alkylsulfanyl, C3-7 cycloalkylsulfanyl or heterocycloalkylsulfanyl lower； (15) C1-7 alkylsulfinyl, C3-7 cycloalkylsulfinyl or lower heterocycloalkylsulfinyl； (16) C1-7 alkylsulfonyl, C3-7 cycloalkylsulfonyl or lower heterocycloalkyl sulfonyl； (17) C1-7 alkylcarbonylamino； (18) C1-7 alkylsulfonylamino； (19) C1-7 dialkylamino, and (20) C1-7 trialkylsilyl； wherein at least one of R2 or R3 is a different fraction of hydrogen, and n is 1 or 2, in which "lower heterocycloalkyl" refers to a partially unsaturated or saturated non-aromatic ring fraction having 3 at 7 ring atoms joined together to form a structure of ring atoms, in which one, two or three of the ring atoms is a heteroatom, while the remaining ring atoms are carbon atoms； "lower heterocycloalkyloxy" refers to an R'-O- fraction, wherein R 'is lower heterocycloalkyl as defined above； "lower heterocycloalkylsulfanyl" refers to a fraction -S-R, wherein R is lower heterocycloalkyl as defined above； "lower heterocycloalkylsulfinyl" refers to a -S (O) -R fraction, wherein R is lower heterocycloalkyl as defined above； and "lower heterocycloalkyl sulfonyl" refers to a fraction -S (O) 2-R, wherein R is lower heterocycloalkyl as defined above.Compuesto de fórmula I **Fórmula** o sales farmacéuticamente aceptables y ésteres del mismo, en la
