Kazuo Hattori,Satoshi Niizuma,Takehiro Okada,Hiroyuki Eda,Kenji Tatsuno,Miyuki Yoshida
申请号:
US10588611
公开号:
US08143274B2
申请日:
2005.02.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides: a compound represented by the following formula (I):[wherein Y1 and Y4 represent a hydrogen atom or a halogen atom either one of Y2 and Y3 represents —NR1R2, and the other represents a hydrogen atom or a halogen atom X represents an aryl group or a heteroaryl group that may be substituted R1 represents a hydrogen atom, or a C1-8 alkyl group that may be substituted and R2 represents a C1-8 alkyl group that is substituted with one or more substituents, —COOR3, —COR4, —COSR5, —CONR6R7, —NR22R23, or —C═NR24R25 or R1 and R2, together with a nitrogen atom to which they are bonded, may form a 4- to 10-membered hetero ring containing at least one nitrogen atom (wherein the hetero ring may be substituted with one or more substituents selected from Group C)], a prodrug thereof, or a pharmaceutically acceptable salt thereof and a pharmaceutical, a pharmaceutical composition, or the like, which comprises the compound.