Class- and isoform-specific HDAC inhibitors and uses thereof

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专利权人:

James Elliot Bradner;Ralph Mazitschek

发明人:

Ralph Mazitschek,James Elliot Bradner

申请号：

US13389814

公开号：

US08716344B2

申请日:

2010.08.11

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to compounds of the following formulawherein R3 is a fluorescent tag. Another aspect of the invention provides an assay for determining the inhibitory effect of a test compound on an HDAC protein comprising: incubating the HDAC protein with a substrate of the above formula in the presence of a test compound； and determining the activity of the HDAC protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/