Abiomed, Inc.;Massachusetts Institute of Technology;The Brigham and Women's Hospital Inc.
发明人:
Ahmad El Katerji,Qing Tan,Christian Moyer,Alexander Ship,Sonya Sanat Bhavsar,Noam Josephy,Elazer R. Edelman,Brian Yale Chang,Steven Keller
申请号:
US16446419
公开号:
US20200086022A1
申请日:
2019.06.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.