Substituted indazole derivatives of formula (I) or formula 2.(I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed； the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.本發明揭示如本說明書中所定義的式(I)或式2.(I)之經取代吲唑衍生物及其醫藥學上可接受之鹽，其等製備方法及包含其等之醫藥組合物；本發明化合物可適用於治療與蛋白激酶活性失調有關之疾病，如癌症。
