The present invention provides a manufacturing method of a mold for a microneedle which can manufacture a high quality microneedle having a very sharp tip and a smooth surface at a high density, has a high design freedom degree of the microneedle and consists of a low costs and simple process, thereby facilitating mass production. The manufacturing method according to the present invention comprises a mold manufacturing step of using an optical mask in which a liquid lens is formed in a light transmitting region, and exposing and developing a base material including a photosensitive layer, thereby manufacturing a mold having a microneedle shape or a reverse phase pattern of the microneedle according to a focusing path of light by the lens during exposure.본 발명은 마이크로니들용 몰드의 제조방법에 관한 것으로, 본 발명에 따른 제조방법은 투광 영역에 액체 렌즈가 형성된 광 마스크를 이용하고 감광층을 포함하는 기재를 노광 및 현상하여, 노광시 렌즈에 의한 광의 집속 경로에 따른 마이크로 니들 형상 또는 마이크로 니들의 역상의 패턴을 갖는 몰드를 제조하는 몰드 제조 단계；를 포함한다.
