VLAHOV, Iontcho R.,LEAMON, Christopher P.,LOW, Philip S.,PARHAM, Garth L.,CHEN, Qingshou
申请号：
EP14861854
公开号：
EP3069147A4
申请日:
2014.11.13
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Described herein are compounds, compositions, and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B-L-P, wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate), PSMA binding ligands, or PSMA inhibitors L is a divalent linker comprising aspartic acid, lysine, or arginine, and P is a radical of an imaging agent or radiotherapy agent, such as a radionuclide or radionuclide containing group, or a radical of a compound capable of binding a radionuclide, such as a metal chelating group.
