VLAHOV IONTCHO R,LEAMON CHRISTOPHER P,LOW PHILIP S,PARHAM GARTH L,CHEN QINGSHOU
申请号:
IN201617019424
公开号:
IN201617019424A
申请日:
2016.06.06
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Described herein are compounds compositions and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B L P wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate) PSMA binding ligands or PSMA inhibitors; L is a divalent linker comprising aspartic acid lysine or arginine and P is a radical of an imaging agent or radiotherapy agent such as a radionuclide or radionuclide containing group or a radical of a compound capable of binding a radionuclide such as a metal chelating group.