Kenneth W. Lyles,Cathleen S. Colon-Emeric,Christopher M. OConnor,Dennis Abraham,Kent Nilson,Howard Rockman,Graham Russell
申请号:
US14358468
公开号:
US20140296166A1
申请日:
2012.11.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides for methods and compositions for treating, reducing and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, prodrug thereof, functional analogue or a pharmaceutically effective salt thereof in an amount sufficient to increase activity of at least one kinase in heart tissue of the subject.